What is NCBN?

  • What is the National Center Biobank Network (NCBN)?

    The National Center (NC) in Japan has a biobank, which stores biological samples such as blood, DNA, and tissues, as well as medical information such as test results and drug prescription histories.
    These samples and information are provided to universities, research institutes, and companies for future medical and healthcare purposes, including the development of new treatments, testing methods, and new drugs, as well as the elucidation of disease states.

    Each NC's biobank is a disease biobank, collecting samples and clinical information on diseases according to each NC's specialty.

    Taking advantage of the expertise of each biobank, we are working together to address a wide range of diseases, and have established a biobank network to provide samples and clinical information in an efficient manner.

    This is the National Center Biobank Network (NCBN).

    For more information, please see "Our Activities".
    You can also watch a video of NCBN activities. Please also see here.

What NC?

About Consent

Sample and clinical information

  • What disease samples are available?
    Do you have samples other than blood?

    The biobank mainly registers samples related to cancer, cardiovascular diseases, psychiatric, neuromuscular diseases, infectious diseases, metabolic diseases, immune disorders, etc., adult diseases, and geriatric diseases in each NC's area of expertise.

    Blood collected from biobank registrants is mainly processed into plasma, serum, and DNA, and then stored at each NC. In addition, test residual samples collected during medical examinations are also stored. Depending on the disease, surgically removed tissue, muscle tissue, spinal fluid, etc. are also stored. Medical information can be provided from the electronic medical record, including laboratory information and drug prescription history, in addition to common medical questions and disease names at the time of registration.

About Storage method

  • How are the samples processed and stored after collection?
    Do you have SOPs?

    The processing and storage methods of samples from collection to storage are properly preserved according to the standard operating procedures (SOP) determined at each NC.
    Details of SOPs for the management of collected samples at each NC can be found under "Protocols and SOP".

About healthy samples

  • Do you have samples/clinical information from healthy?
    Can I use them for my research?

    Although NCBN is a disease-based biobank, we also hold samples from people who have undergone physical examinations and trauma patients, which may be treated as healthy people for some studies. Please contact the Central Biobank for the required samples.

How to search

  • NCBN has 6 biobanks, do you know which NC has the desired sample?

    The NCBN has released a "Catalog Database" that allows you to search catalog information such as which NC has what kind of disease samples.

    NCBN does not impose any conditions on the use of the catalog database in order to make it available to the public. We hope you will make use of it.
    Please refer to "Searchable Items" for items that can be searched in the catalog database.

Terms of Use

  • What conditions apply to the use of samples and clinical information?
    Can companies use the samples and information?

    NCBN's samples can be provided to companies, research institutes, and universities in Japan for a fee or in the form of joint research. Currently, we do not offer paid provision to companies and research institutions outside of Japan, but we may be able to provide them in the form of joint research.

    In collaborative research, NCI will provide samples and information for research conducted jointly by NCI researchers and researchers from universities, research institutes, and companies in Japan and overseas.
    In the case of paid donation, NC will provide samples and information for research conducted by non-NC research institutions, including private companies, under an MTA (Material Transfer Agreement).
    The type of MTA depends on the NC and the samples to be provided, so please contact the Central Biobank.

    Please refer to "Matters Related to Research Utilization" for the MTA and other common application forms.

About Costs

  • How much will it cost to provide the service?

    In the case of distribution, the actual cost of consumables such as tubes and reagents used for sample collection will be charged. For specific amounts, please check with each NC individually as we are not able to standardize costs due to the fact that some NCs are not yet ready to distribute.

    Please use the "Catalog Database" to check the conditions of use to see if subdivision is possible.

How to apply

  • How do I apply to use NCBN samples and clinical information?

    Please contact the Central Biobank Office through the "Contact Us" page.
    We will match you with an NC biobank that has your samples based on the content of your inquiry. At that time, we will provide you with detailed information about each NC biobank and how to provide the samples.
    After a hearing, we will ask you to submit a research plan, an application form, a copy of the ethics review approval form, and other necessary documents, and a committee that reviews the use of biobank materials and information will review the validity of the research and the eligibility of the research institution.
    Depending on the method of donation and samples, approval by the Ethics Review Committee of each NC may be required.

Provision of Infectious Disease Samples

  • Can you provide samples of infectious diseases and bacteria?

    For samples of infectious diseases and bacteria, contact the NCGM(National Center for Global Health and Medicine) Biobank. (ncgmbb@hosp.ncgm.go.jp)